FPGEE for National Association of Boards of Pharmacy (NABP) Practice Exam 2025 - Free NABP Practice Questions and Study Guide

An Arrhenius base is defined by its ability to produce hydroxide ions (OH-) when dissolved in water. This characteristic distinguishes it from other types of bases. In the context of aqueous solutions, when an Arrhenius base is dissolved, it dissociates to release OH- ions, thereby increasing the concentration of hydroxide in the solution and contributing to basic properties.

The production of OH- ions is fundamental to the Arrhenius concept of acids and bases, formulated by Svante Arrhenius in the late 19th century. According to this theory, bases that generate hydroxide ions in water can effectively neutralize acids, which produce hydrogen ions (H+) in solution. The reaction between an acid and an Arrhenius base leads to the formation of water and a salt, exemplifying the neutralization process.

Understanding this concept is essential for working in pharmaceutical sciences and other chemical disciplines, where the behavior of acids and bases can significantly impact drug formulation, stability, and activity.