FPGEE for National Association of Boards of Pharmacy (NABP) Practice Exam 2026 - Free NABP Practice Questions and Study Guide

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What does a score of 9-10 on the Naranjo ADR Probability Scale indicate?

Doubtful that drug caused an ADR

Possible causation of an ADR

Probable causation of an ADR

Highly probable causation of an ADR

A score of 9-10 on the Naranjo ADR Probability Scale indicates that there is highly probable causation of an adverse drug reaction (ADR). This scale is designed to assess the likelihood that a drug is the cause of an adverse event.

In the context of the Naranjo scale, scores are assigned based on specific criteria that consider factors such as the timing of the ADR in relation to drug administration, the presence of previous reactions, and the response to the drug when it is re-administered. A higher score correlates with stronger evidence supporting the relationship between the drug and the observed adverse effect.

Thus, a score in the range of 9 to 10 suggests substantial evidence that the drug is not only linked to the ADR but that other potential causes are unlikely. This scoring nuance underscores the importance of rigorous evaluation in pharmacovigilance and clinical practice, as it guides healthcare professionals in making informed decisions regarding drug safety and patient care.

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